spiral ganglion การใช้

• Type II spiral ganglion cells make up the remainder.
• Two apparent subtypes of spiral ganglion cells exist.
• The depolarized hair cell releases neurotransmitters across a synapse to primary auditory neurons of the spiral ganglion.
• It was found that some months after the organ of Corti had degenerated, the spiral ganglion also began to degenerate.
• Upon reaching receptors on the postsynaptic spiral ganglion neurons, the neurotransmitters induce a postsynaptic potential or generator potential in the neuronal projections.
• Each fiber is an axon of a spiral ganglion cell that represents a particular frequency of sound, and a particular range of loudness.
• When a certain threshold potential is reached, the spiral ganglion neuron fires an action potential, which enters the auditory processing pathway of the brain.
• The cell bodies of the cochlear nerve lie within the cochlea and collectively form the spiral ganglion, named for the spiral shape it shares with the cochlea.
• In addition, outer hair cells form reciprocal synapses onto Type II spiral ganglion cells, suggesting that the Type II cells have both afferent and efferent roles.
• Kcne3 deletion also impairs auditory function because of the loss of regulation of Kv4.2 channels by KCNE3 in spiral ganglion neurons ( SGNs ) of the auditory system.
• Type I spiral ganglion cells comprise the vast majority of spiral ganglion cells ( 90-95 % in cats and 88 % in humans ), and exclusively innervate the inner hair cells.
• Type I spiral ganglion cells comprise the vast majority of spiral ganglion cells ( 90-95 % in cats and 88 % in humans ), and exclusively innervate the inner hair cells.
• In the mammalian brain, MVR has been shown to be common in CA1 pyramidal cells and Schaffer collateral cells . and then refuted at the ribbon synapses formed between inner hair cell and spiral ganglion neurons.
• This causes the cell to depolarise, and creates an action potential that is transmitted along the spiral ganglion, which sends information through the auditory portion of the vestibulocochlear nerve to the temporal lobe of the brain.
• In the developing auditory system, developing cochlea generate bursts of activity which spreads across the inner hair cells and spiral ganglion neurons which relay auditory information to the brain . cortex, early waves of activity have been observed in the cerebellum and cortical slices.
• The outer hair cells ( OHC ) are minimally innervated by spiral ganglion in slow ( unmyelinated ) reciprocal communicative bundles ( 30 + hairs per nerve fiber ); this contrasts inner hair cells ( IHC ) that have only afferent innervation ( 30 + nerve fibers per one hair ) but are heavily connected.
• The sound waves vibrate the tympanic membrane ( ear drum ), causing the three bones of the middle ear to vibrate, which then sends the energy through the oval window and into the cochlea where it is changed into a chemical signal by hair cells in the organ of corti, which synapse onto spiral ganglion fibers that travel through the cochlear nerve into the brain.